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Review
. 2021 Jan-Feb;10(1):19-24.
doi: 10.4103/eus.eus_23_20.

EUS-through-the-needle microbiopsy forceps in pancreatic cystic lesions: A systematic review

Vasile Daniel Balaban  1 , Irina M Cazacu  2 , Larisa Pinte  3 , Mariana Jinga  1 , Manoop S Bhutani  4 , Adrian Saftoiu  5
Affiliations
Review

EUS-through-the-needle microbiopsy forceps in pancreatic cystic lesions: A systematic review

Vasile Daniel Balaban et al. Endosc Ultrasound. 2021 Jan-Feb.

Abstract

Pancreatic cystic lesions (PCLs) are being increasingly encountered in clinical practice, and sometimes, they can represent a diagnostic challenge. Recently, a through-the-needle micro forceps biopsy (MFB) device was introduced in the endosonography practice to facilitate EUS-guided sampling of PCLs. The aim was to perform a systematic review of studies evaluating the technical aspects, safety, and efficacy of the EUS-guided MFB for PCLs. A literature search was performed in three major databases, PubMed, Embase, and Web of Science in September 2019 using the search terms: "through-the-needle," "biopsy forceps," "microforceps," "endoscopic ultrasound," and "endosonography." Case reports and case series with <10 patients were excluded from the analysis. Altogether nine studies reporting on 463 patients were included in our systematic review. The mean age of the patients was 68.3 years, with a slight female predominance (60.9%). Most of the cysts were located in the body/tail of the pancreas (61.2%), with an overall mean size of 33 mm. The technical success of EUS-guided MFB was reported in 98.5%. The tissue acquisition yield reported was 88.2%, and the diagnostic accuracy was 68.6%. Adverse events were reported in 9.7%. EUS-guided MFB is technically feasible, safe, and has a high diagnostic accuracy for PCLs.

Keywords: EUS; diagnostic accuracy; microbiopsy forceps; pancreatic cyst.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
PRISMA 2009 flow diagram
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