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Case Reports
. 2020 Jun 16:2020:8685126.
doi: 10.1155/2020/8685126. eCollection 2020.

Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica

Rong Guo  1 , Mingming Zhou  1 , Xiaohui Wei  1 , Ling Niu  1
Affiliations
Case Reports

Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica

Rong Guo et al. Can Respir J. .

Abstract

Objective: To investigate the clinical characteristics of tracheobronchopathia osteochondroplastica (TO).

Methods: The clinical data of six patients with TO from November 2016 to November 2018 were retrospectively analyzed. The etiology, clinical manifestations, diagnosis, and treatment of TO were summarized.

Result: All six patients with TO were middle-aged males, confirmed by histopathological examination. The main clinical symptoms were cough, sputum, hemoptysis, chest pain, and repeated pulmonary infection. Some patients could make a preliminary diagnosis by chest CT, and bronchoscopy showed that TO mainly occurred in the trachea and the main bronchus and was more likely to invade the right bronchus. The treatment mainly includes anti-infection, phlegm-resolving, and other symptomatic treatment.

Conclusion: TO is a benign disease predisposing to adults, and males are more likely to be affected. Its clinical manifestations are lack of specificity, and the cause may be related to chronic infection. Bronchoscopy combined with histopathological examination is the primary approach for the diagnosis of TO. There is no well-recognized treatment standard for TO, and the judgment of therapeutic effect is inconsistent. It is necessary to improve the understanding of this disease from a clinical perspective.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Case 3 lung CT: multiple ring calcifications in main bronchi walls.
Figure 2
Figure 2
Case 4 (a) bronchoscopic examination: multiple nodular tuberositas of the lower trachea, the surface is uneven and pebble-like, part fuse into pieces. (b) Bronchoscopic examination: multiple nodular tuberositas of the tracheal carina and left and right main bronchus and some surfaces are covered with yellow pus. (c) Hematoxylin and eosin (H&E) stain at 100x magnification: pathological results of tracheal nodules, partial squamous cells on the bronchial mucosa epithelium, a large number of lymphocytes, plasma cells, and partial ossification.
See this image and copyright information in PMC

References

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