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Review
. 2020 Jun 17:24:41-48.
doi: 10.1016/j.ctro.2020.06.007. eCollection 2020 Sep.

ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer

Felipe A Calvo  1   2   3 , Claudio V Sole  4   3 , Harm J Rutten  5   6 , Wim J Dries  7 , Miguel A Lozano  8 , Mauricio Cambeiro  1 , Philip Poortmans  9   10 , Luis González-Bayón  3   11
Affiliations
Review

ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in locally recurrent rectal cancer

Felipe A Calvo et al. Clin Transl Radiat Oncol. .

Erratum in

Abstract

Multimodal strategies have been implemented for locally recurrent rectal cancer scheduled for complete surgical resection. Irradiation and systemic therapy have been added to improve the oncological outcome, as surgery alone was associated with a poor prognosis. Intraoperative irradiation (IORT) is a component of irradiation intensification. Long-term cancer control and a higher survival rate were consistently reported in patients who had IORT as a component of their multidisciplinary treatment. The experience reported by expert IORT groups is reviewed and recommendations to guide clinical practice are explained in detail.

Keywords: Electron beam; Intraoperative radiotherapy; Oligo-recurrence; Rectal cancer; Recurrent disease; Rescue surgery.

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Figures

Fig. 1
Fig. 1
IORT electron procedure view of a recurrent rectal cancer with associated uretero-hidronefrosis: A. Pelvic cavity exposed and right ureteral dilatation. B. Simulated IOERT applicator positioning to treat recurrent tumor bed. The involved ureter is included in the treatment volume. C. Post-resection recurrent tumor bed area to be treated by IOERT. The right ureter has been sectioned and mobilized out of the electron beam collimator. After irradiation an uretero-ureteral anastomosis to the left ureter will be performed for urinary tract reconstruction.
See this image and copyright information in PMC

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