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Comment
. 2020 Nov;21(11):1022-1023.
doi: 10.1097/PCC.0000000000002513.

Coronavirus Disease 2019: Understanding Immunopathogenesis Is the "Holy Grail" to Explain Why Children Have Less Severe Acute Disease

Vanessa Soares Lanziotti  1 , Daniela Carla de Souza  2 , Ernesto T A Marques  3
Affiliations
Comment

Coronavirus Disease 2019: Understanding Immunopathogenesis Is the "Holy Grail" to Explain Why Children Have Less Severe Acute Disease

Vanessa Soares Lanziotti et al. Pediatr Crit Care Med. 2020 Nov.
No abstract available

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Conflict of interest statement

Dr. Marques received support for article research from the National Institutes of Health. The remaining authors have disclosed that they do not have any potential conflicts of interest.

Figures

Figure 1.
Figure 1.
Possible mechanisms explaining why children’s acute clinical presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less severe. ACE2 = angiotensin-converting enzyme 2, ADE = antibody-dependent enhancement, COVID-19 = coronavirus disease 2019, S protein = spike protein.
See this image and copyright information in PMC

Comment in

  • The authors reply.
    Ong JSM, Tosoni A, Kim Y, Kissoon N, Murthy S. Ong JSM, et al. Pediatr Crit Care Med. 2020 Nov;21(11):1023. doi: 10.1097/PCC.0000000000002569. Pediatr Crit Care Med. 2020. PMID: 32925565 Free PMC article. No abstract available.

Comment on

References

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