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Comment
. 2020 Jul 2;27(1):8-10.
doi: 10.1016/j.stem.2020.06.008.

From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

Malin Parmar  1 , Anders Björklund  2
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From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

Malin Parmar et al. Cell Stem Cell. .
Free article

Abstract

In a pioneering study in New England Journal of Medicine, Schweitzer et al. (2020) report on a patient with Parkinson's disease who received a graft of dopamine neurons obtained from in vitro differentiated induced pluripotent stem cells, derived from the patient's own skin fibroblasts, showing the feasibility of autologous transplantation for dopamine cell replacement.

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Conflict of interest statement

Declaration of Interests M.P. is the owner of Parmar Cells AB and co-inventor of the US patent application 15/093,927 owned by Biolamina AB, 16/610,787 owned by New York Stem Cell Foundation, and EP17181588 owned by Miltenyi Biotec. M.P. receives research funding from Novo Nordisk.

Comment on

  • Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease.
    Schweitzer JS, Song B, Herrington TM, Park TY, Lee N, Ko S, Jeon J, Cha Y, Kim K, Li Q, Henchcliffe C, Kaplitt M, Neff C, Rapalino O, Seo H, Lee IH, Kim J, Kim T, Petsko GA, Ritz J, Cohen BM, Kong SW, Leblanc P, Carter BS, Kim KS. Schweitzer JS, et al. N Engl J Med. 2020 May 14;382(20):1926-1932. doi: 10.1056/NEJMoa1915872. N Engl J Med. 2020. PMID: 32402162 Free PMC article.

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