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Review
. 2020 Aug;24(3):405-419.
doi: 10.1016/j.cld.2020.04.008. Epub 2020 Apr 13.

Viral Hepatitis Other than A, B, and C: Evaluation and Management

Amanda Cheung  1 , Paul Kwo  2
Affiliations
Review

Viral Hepatitis Other than A, B, and C: Evaluation and Management

Amanda Cheung et al. Clin Liver Dis. 2020 Aug.

Abstract

Viral hepatitis can cause a wide spectrum of clinical presentations from a benign form with minimal or no symptoms to acute liver failure or death. Hepatitis D coinfection and superinfection have distinct clinical courses, with the latter more likely leading to chronic infection. Management of chronic hepatitis D virus is individualized because of the paucity of treatment options and significant side effect profile of currently available treatments. Sporadic cases of hepatitis E caused by contaminated meats are becoming increasingly prevalent in immunocompromised hosts. Human herpesviruses are an important cause of disease also in immunocompromised individuals.

Keywords: Hepatitis D; Hepatitis E; Hepatotropic viruses; Human herpesvirus; Viral hepatitis.

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Conflict of interest statement

Disclosure A. Cheung has nothing to disclose. P. Kwo has received grant support from Eiger.

Figures

Fig. 1
Fig. 1
Typical pattern of HBV and HDV serologies in HDV infection. Coinfection leads to clearance of both viruses in 95% of patients. Superinfection in a patient with preexisting chronic HBV infection most often leads to chronic HDV infection. HBcAb, hepatitis B core antibody; HBsAb, hepatitis B surface antibody; IgG, immunoglobulin G; IgM, immunoglobulin M.
See this image and copyright information in PMC

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MeSH terms