Demystifying pulmonary vascular complications in severe coronavirus disease-19 pneumonia (COVID-19) in the light of clinico-radiologic-pathologic correlation
- PMID: 32620455
- PMCID: PMC7319924
- DOI: 10.1016/j.thromres.2020.06.043
Demystifying pulmonary vascular complications in severe coronavirus disease-19 pneumonia (COVID-19) in the light of clinico-radiologic-pathologic correlation
Abstract
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Small pulmonary vessel changes are a unique imaging feature of COVID-19 pneumonia.
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Autopsy studies reveal a very high incidence of peripheral pulmonary thrombosis.
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Risk of thrombosis is high in severe COVID-19 despite anticoagulation.
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Mounting evidence suggests immunothrombosis as a contributory cause of thrombosis.
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Combined inflammation reduction and anticoagulation seems to be a rational therapeutic protocol.
Comment on
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Segmental Pulmonary Vascular Changes in COVID-19 Pneumonia.AJR Am J Roentgenol. 2020 Sep;215(3):W33. doi: 10.2214/AJR.20.23443. Epub 2020 May 8. AJR Am J Roentgenol. 2020. PMID: 32383969 No abstract available.
References
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- Parry A.H., Wani A.H. Segmental pulmonary vascular changes in COVID-19 pneumonia. American Journal of Roentgenology. 2020 May 8:W1- - PubMed
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- Moores L.K., Tritschler T., Brosnahan S., Carrier M., Collen J.F., Doerschug K., Holley A.B., Jimenez D., LeGal G., Rali P., Wells P. Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report. Chest. 2020 Jun;2
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