Azithromycin and SARS-CoV-2 infection: Where we are now and where we are going
- PMID: 32622008
- PMCID: PMC7328586
- DOI: 10.1016/j.jgar.2020.06.016
Azithromycin and SARS-CoV-2 infection: Where we are now and where we are going
Abstract
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Azithromycin (AZM) is a promising drug candidate for the treatment of the COVID-19.
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Studies so far on the use of AZM in COVID-19 patients have various methodological limitations.
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The evidence on the efficacy of AZM as an adjunct to hydroxychloroquine for COVID-19 is not enough yet.
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Combination of AZM and HCQ should be decided with caution due serious cardiac adverse effects.
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Currently, 21 clinical trials are being carried out on the use of AZM in COVID-19.
Keywords: Azithromycin; COVID-19; Clinical trial; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2.
Comment on
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RETRACTED: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.Int J Antimicrob Agents. 2020 Jul;56(1):105949. doi: 10.1016/j.ijantimicag.2020.105949. Epub 2020 Mar 20. Int J Antimicrob Agents. 2020. Retraction in: Int J Antimicrob Agents. 2025 Jan;65(1):107416. doi: 10.1016/j.ijantimicag.2024.107416. PMID: 32205204 Free PMC article. Retracted. Clinical Trial.
References
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- Gautret P., Lagier J.-C., Parola P., Hoang V.T., Meddeb L., Mailhe M. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents. 2020;(March) doi: 10.1016/j.ijantimicag.2020.105949. [Epub ahead of print] - DOI - PMC - PubMed
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