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. 2020 Aug:166:108293.
doi: 10.1016/j.diabres.2020.108293. Epub 2020 Jul 3.

Risk factors for mortality among COVID-19 patients

Orwa Albitar  1 , Rama Ballouze  2 , Jer Ping Ooi  3 , Siti Maisharah Sheikh Ghadzi  1
Affiliations

Risk factors for mortality among COVID-19 patients

Orwa Albitar et al. Diabetes Res Clin Pract. 2020 Aug.

Abstract

Aims: COVID-19 is a current global pandemic. However, comprehensive global data analyses for its mortality risk factors are lacking. The current investigation aimed to assess the predictors of death among COVID-19 patients from worldwide open access data.

Methods: A total of 828 confirmed cases of COVID-19 with definite outcomes were retrospectively identified from open access individual-level worldwide data. Univariate followed by multivariable regression analysis were used to evaluate the association between potential risk factors and mortality.

Results: Majority of the patients were males 59.1% located in Asia 69.3%. Based on the data, older age (adjusted odds ratio (aOR), 1.079; 95% confidence intervals (95% CI), 1.064-1.095 per year increase), males (aOR, 1.607; 95% CI, 1.002-2.576), patients with hypertension (aOR, 3.576; 95% CI, 1.694-7.548), diabetes mellitus (aOR, 12.234; 95% CI, 4.126-36.272), and patients located in America (aOR, 7.441; 95% CI, 3.546-15.617) were identified as the risk factors of mortality among COVID-19 patients.

Conclusions: Males, advanced age, hypertension patients, diabetes mellitus patients, and patients located in America were the independent risk factors of death among COVID-19 patients. Extra attention is required to be given to these factors and additional studies on the underlying mechanisms of these effects.

Keywords: COVID-19; Cross-sectional; Mortality; Outcome; Risk factors.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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