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. 2019 May 10;17(5):e05702.
doi: 10.2903/j.efsa.2019.5702. eCollection 2019 May.

Assessment of the application for renewal of the authorisation of PHYZYME®XP 10000 TPT/L (6-phytase) as a feed additive for all avian species and all swine species

EFSA Panel on Additives and Products or Substances used in Animal Feed (EFSA FEEDAP Panel); Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Kos Durjava, Marta López-Alonso, Secundino López Puente, Francesca Marcon, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Montserrat Anguita, Elisa Pettenati, Baltasar Mayo

Assessment of the application for renewal of the authorisation of PHYZYME®XP 10000 TPT/L (6-phytase) as a feed additive for all avian species and all swine species

EFSA Panel on Additives and Products or Substances used in Animal Feed (EFSA FEEDAP Panel) et al. EFSA J. .

Abstract

PHYZYME ® XP 10000 TPT/L is a feed additive that contains 6-phytase produced by a genetically modified strain of Schizosaccharomyces pombe. The applicant requested for the renewal of the authorisation for PHYZYME ® XP 10000 TPT and L to be used as a feed additive for avian species for fattening/laying, weaned piglets, pigs for fattening and sows and for an extension of use to avian species reared for laying/breeding, suckling piglets and minor porcine species. To support the request or the renewal of the authorisation, the applicant provided evidence that the additive in the market complies with the conditions of the authorisation. According to the information provided by the applicant, no new evidence has been identified that would make the FEEDAP Panel reconsider the previous conclusions regarding the safety for the target species, consumer, user and environment. The application for renewal of the authorisation did not include a proposal for amending the conditions of use in those species for which an authorisation exists that would have an impact on the efficacy of the additive. Therefore, there was no need for assessing the efficacy of the additive in the context of the renewal of the authorisation. Regarding the new species/categories, the Panel concluded that the additive is safe and has a potential to be efficacious in avian species reared for laying/breeding at 250 FTU/kg feed and for suckling piglets and minor porcine species at 500 FTU/kg feed.

Keywords: digestibility enhancers; efficacy; phytase; pigs; poultry; safety; zootechnical additives.

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References

    1. EFSA (European Food Safety Authority), 2006a. Opinion of the Scientific Panel on Additives and Products or Substances used in Animal Feed and the Scientific Panel on Genetically Modified Organisms on the safety and efficacy of Phyzyme XP 5000 (G/L), 6‐phytase) as a feed additive for chickens for fattening. EFSA Journal 2006;4(5):350, 14 pp. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2006.350/epdf - DOI
    1. EFSA (European Food Safety Authority), 2006b. Opinion of the Scientific Panel on Additives and Products or Substances used in Animal Feed and the Scientific Panel on Genetically Modified Organisms on the safety and efficacy of Phyzyme XP 5000 (G/L), 6‐phytase) as a feed additive for chickens for fattening, laying hens, turkeys for fattening, ducks for fattening, piglets (weaned), pigs for fattening and sows. EFSA Journal 2006;4(10):404, 20 pp. https://www.efsa.europa.eu/en/efsajournal/pub/404
    1. EFSA (European Food Safety Authority), 2007. Opinion of the Scientific Committee on a request from EFSA on the introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA. EFSA Journal 2007;5(12):587, 16 pp. 10.2903/j.efsa.2007.587 - DOI
    1. EFSA (European Food Safety Authority), 2008. Safety and efficacy of Phyzyme XP 10000 (TPT/L), 6‐phytase as a feed additive for chickens for fattening, laying hens, turkeys for fattening, ducks for fattening, piglets (weaned), pigs for fattening and sows. EFSA Journal 2008;6(12):915, 10 pp. 10.2903/j.efsa.2008.915 - DOI
    1. EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), 2017. Scientific Opinion on the update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA. EFSA Journal 2017;15(3):4664, 177 pp. 10.2903/j.efsa.2017.4664 - DOI - PMC - PubMed