Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jun 11:2020:1243947.
doi: 10.1155/2020/1243947. eCollection 2020.

Age-Period-Cohort Analysis of Type 2 Diabetes Mortality Attributable to Particulate Matter Pollution in China and the U.S

Affiliations

Age-Period-Cohort Analysis of Type 2 Diabetes Mortality Attributable to Particulate Matter Pollution in China and the U.S

Xiaoxue Liu et al. J Diabetes Res. .

Abstract

Aim: We aimed to assess and compare secular trends in type 2 diabetes mortality attributable to particulate matter pollution in China and U.S.

Methods: We performed an age-period-cohort (APC) analysis to estimate the independent effects of age, period, and cohort on mortality of type 2 diabetes attributable to particulate matter pollution. We collected age-standardized and age-specific mortality rates (1990-2017) from the Global Burden of Disease 2017 Study for China and the U.S.

Results: During the period 1990-2017, the age-standardized mortality rates of type 2 diabetes attributable to particulate matter pollution in China showed a general increasing trend, while that in U.S. showed an increase before 2002 and subsequently a decrease. The age effect increased markedly in China compared with the U.S. The period effect showed a substantially increase in China while that in the U.S. increased during 1990-2007 and tended to be stable during 2007-2017. The cohort effect peaked in birth cohort born in 1902-1906 in both China and U.S. and declined consistently in the cohort born in 1992-1996.

Conclusions: The age-standardized mortality rates of type 2 diabetes attributable to particulate matter pollution, the age, and period effect in China have been increasing in both sexes from 1990 to 2017. The overall mortality in the U.S. began to decrease since 2003, and the period effect showed a tendency to stabilize. Consequently, it is necessary to educate the nation with the correct knowledge and adopting policies on pollutant emission and techniques to reduce air pollution in China.

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
Type 2 diabetes mortality attributable to particulate matter pollution relative risks due to (a) age, (b) period, and (c) cohort effects. The left graph is China, and the right is the U.S.
Figure 2
Figure 2
Trends in the age-standardized rates of type 2 diabetes attributable to particulate matter pollution in China and the U.S. from 1990-2017, at all ages. (a) China; (b) U.S.

References

    1. Zimmet P. Z., Magliano D. J., Herman W. H., Shaw J. E. Diabetes: a 21st century challenge. The Lancet Diabetes and Endocrinology. 2014;2(1):56–64. doi: 10.1016/S2213-8587(13)70112-8. - DOI - PubMed
    1. Zimmet P., Alberti K. G., Magliano D. J., Bennett P. H. Diabetes mellitus statistics on prevalence and mortality: facts and fallacies. Nature Reviews. Endocrinology. 2016;12(10):616–622. doi: 10.1038/nrendo.2016.105. - DOI - PubMed
    1. Tuomi T., Santoro N., Caprio S., Cai M., Weng J., Groop L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet. 2014;383(9922):1084–1094. doi: 10.1016/S0140-6736(13)62219-9. - DOI - PubMed
    1. Zhou B., Lu Y., Hajifathalian K., et al. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population- based studies with 4·4 million participants. Lancet. 2016;387(10027):1513–1530. doi: 10.1016/S0140-6736(16)00618-8. - DOI - PMC - PubMed
    1. GBD 2017 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1859–1922. doi: 10.1016/S0140-6736(18)32335-3. - DOI - PMC - PubMed

Substances