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Comment
. 2020 Oct;598(19):4153-4154.
doi: 10.1113/JP280253. Epub 2020 Jul 23.

Clash of the cascades: Release the inhibition

Brad S Currier  1 , Sophie Joanisse  1 , James McKendry  1
Affiliations
Free article
Comment

Clash of the cascades: Release the inhibition

Brad S Currier et al. J Physiol. 2020 Oct.
Free article
No abstract available

Keywords: AMPK; glycogen; mTOR; protein synthesis; resistance exercise.

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References

    1. Dreyer HC, Fujita S, Cadenas JG, Chinkes DL, Volpi E & Rasmussen BB (2006). Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J Physiol 576, 613-624.
    1. Knudsen JR, Li Z, Persson KW, Li J, Henriquez-Olguin C & Jensen TE (2020). Contraction-regulated mTORC1 and protein synthesis: Influence of AMPK and glycogen. J Physiol 598, 2637-2649.
    1. Ljubicic V, Adhihetty PJ & Hood DA (2005). Application of animal models: chronic electrical stimulation-induced contractile activity. Can J Appl Physiol 30, 625-643.
    1. West DW, Baehr LM, Marcotte GR, Chason CM, Tolento L, Gomes AV, Bodine SC & Baar K (2016). Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle. J Physiol 594, 453-468.
    1. You JS, McNally RM, Jacobs BL, Privett RE, Gundermann DM, Lin KH, Steinert ND, Goodman CA & Hornberger TA (2019). The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy. FASEB J 33, 4021-4034.

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