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Meta-Analysis
. 2020 Jul 2;99(27):e21031.
doi: 10.1097/MD.0000000000021031.

Guipi decoction for insomnia: Systematic review and meta-analysis

Mao Li  1 , Rui Lan  2 , Yong Wen  1 , Kejin Shi  1 , Dongdong Yang  1
Affiliations
Meta-Analysis

Guipi decoction for insomnia: Systematic review and meta-analysis

Mao Li et al. Medicine (Baltimore). .

Erratum in

  • Study Protocol Titles: Erratum.
    [No authors listed] [No authors listed] Medicine (Baltimore). 2020 Aug 14;99(33):e21984. doi: 10.1097/MD.0000000000021984. Medicine (Baltimore). 2020. PMID: 32872085 Free PMC article. No abstract available.

Abstract

Background: Insomnia is a common sleep disorder with symptoms including difficulty falling asleep and early awakening. Guipi decoction is widely used in clinical treatment of insomnia in China. However, there is a lack of systematic evaluation and analysis of Guipi decoction. Therefore, our study will provide efficacy assessments and adverse events assessments.

Methods: A comprehensive search for randomized controlled trials of Gupi decoction treatments for insomnia will be carried in MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trial (CENTRAL), CINAHL, AMED and Chinese databases include CBM, CNKI, CQVIP, and Wanfang from their inceptions to May 2020. Relevant reference lists, Baidu Scholar and grey literature will also be checked. Two experienced reviewers will independently search all databases. Primary outcomes include Pittsburgh sleep quality index and clinical effective rate, and secondary outcomes include traditional Chinese medicine syndrome, adverse events, and Epworth Sleepiness Scale. Review Manager 5.3 software will be used analyze all data.

Results: This article will be dedicated to assessing the efficacy and safety of Guipi decoction for insomnia.

Conclusion: The conclusion of this systematic review will provide evidence to judge whether Guipi Decoction is an effective therapeutic intervention for patient with insomnia. Maybe these results could potentially be helpful for improving the therapeutic strategy of patients with insomnia.

Prospero registration number: CRD 42020164911.

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Conflict of interest statement

The authors have no conflicts of interests to disclose.

Figures

Figure 1
Figure 1
Flow chart of study selection process.
See this image and copyright information in PMC

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MeSH terms