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Clinical Trial
. 1988 Aug;32(6):502-4.
doi: 10.1111/j.1399-6576.1988.tb02774.x.

The reduction of pain on injection of propofol: the effect of addition of lignocaine

S Helbo-Hansen  1 , V Westergaard, B L Krogh, H P Svendsen
Affiliations
Clinical Trial

The reduction of pain on injection of propofol: the effect of addition of lignocaine

S Helbo-Hansen et al. Acta Anaesthesiol Scand. 1988 Aug.

Abstract

The effects of addition of 1 ml of lignocaine (10 mg) or isotonic saline to 19 ml of the emulsified preparation of propofol (Diprivan) were studied in a randomised, double-blind trial in 80 patients. The incidence and severity of pain on injection of propofol were significantly reduced by the addition of lignocaine (P less than 0.01).

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