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Comparative Study
. 2020 Jun 27;50(3):127-132.
doi: 10.4274/tjo.galenos.2019.14554.

Comparison of Higher-Order Aberrations After Single-Step Transepithelial and Conventional Alcohol-Assisted Photorefractive Keratectomy

Affiliations
Comparative Study

Comparison of Higher-Order Aberrations After Single-Step Transepithelial and Conventional Alcohol-Assisted Photorefractive Keratectomy

Kemal Özülken et al. Turk J Ophthalmol. .

Abstract

Objectives: To compare the asphericity and higher-order aberration (HOA) outcomes of single-step transepithelial photorefractive keratectomy (tPRK) and conventional alcohol-assisted PRK (aaPRK) in patients with myopia and myopic astigmatism.

Materials and methods: Of the 108 eyes of 54 patients enrolled in the study, tPRK was performed on 54 (50%) eyes and aaPRK was performed on 54 (50%) eyes. The following parameters were compared: corrected distance visual acuity (CDVA), spherical equivalent (SE), flat and steep keratometry, intraocular pressure, central corneal thickness, asphericity, and HOAs including horizontal and vertical coma, horizontal and vertical trefoil, spherical aberration, second-order vertical coma, and aberration coefficient.

Results: The demographic and baseline characteristics were similar between the two groups (p>0.05, for all). The aberration coefficient value was significantly lower in patients treated with aaPRK compared to patients treated with tPRK at postoperative 3 months, 6 months, and 1 year (p=0.022, p=0.019, and p=0.017, respectively). Differences in the other variables were statistically insignificant (p>0.05 for all).

Conclusion: Both tPRK and aaPRK procedures obtain similar postoperative CDVA, SE, asphericity, and HOA outcomes, except the aberration coefficient value.

Keywords: Transepithelial photorefractive keratectomy; alcohol-assisted photorefractive keratectomy; asphericity; higher-order aberration; PRK.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Figure 1
Figure 1
The mean corrected distant visual acuity (CDVA) in transepithelial photorefractive keratectomy (tPRK) and alcohol-assisted PRK (aaPRK) groups
Figure 2
Figure 2
The mean manifest refraction spherical equivalents (MRSE) in transepithelial photorefractive keratectomy (tPRK) and alcohol-assisted PRK (aaPRK) groups

References

    1. Clinch TE, Moshirfar M, Weis JR, Ahn CS, Hutchinson CB, Jeffrey JH. Comparison of mechanical and transepithelial debridement during photorefractive keratectomy. Ophthalmology. 1999;106:483–489. - PubMed
    1. Carr JD, Patel R, Hersh PS. Management of late corneal haze following photorefractive keratectomy. J Refract Surg. 1995;11(3 Suppl):309–313. - PubMed
    1. Lee HK, Lee KS, Kim JK, Kim HC, Seo KR, Kim EK. Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser. Am J Ophthalmol. 2005;139:56–63. - PubMed
    1. Aslanides IM, Padroni S, Arba Mosquera S, Ioannides A, Mukherjee A. Comparison of single-step reverse transepithelial all-surface laser ablation (ASLA) to alcohol-assisted photorefractive keratectomy. Clin Ophthalmol. 2012;6:973–980. - PMC - PubMed
    1. Luger MH, Ewering T, Arba-Mosquera S. Consecutive myopia correction with transepithelial versus alcohol-assisted photorefractive keratectomy in contralateral eyes: one-year results. J Cataract Refract Surg. 2012;38:1414–1423. - PubMed

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