Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France

Abstract

Fix data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnant women with SARS-CoV-2 infection in 4 obstetric units in the Paris metropolitan area of France during March 12-April 13, 2020. Among patients, 52 (52%) were hospitalized, 10 (10%) in intensive care units (ICUs). Women with higher body mass indexes (BMIs; median 30.7 kg/m²) were more likely to be hospitalized in ICUs than other women (median BMI 26.2 kg/m²). Women hospitalized in ICUs had lower lymphocyte count at diagnosis (median 0.77 × 10⁹ cells/L) than women not hospitalized in ICUs (median lymphocyte count 1.15 × 10⁹ cells/L). All women requiring oxygen >5 L/min were intubated. Clinical and laboratory evaluation of SARS-CoV-2-positive pregnant women at the time of diagnosis can identify patients at risk for ICU hospitalization.

Keywords: COVID-19; France; MERS; SARS; SARS-CoV-2; coronavirus; coronavirus disease; pregnancy; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Figure

Flowchart of study data showing status and medical referral in a cohort of pregnant women with SARS-CoV-2 infection, France. CT, computed tomography; RT-PCR, reverse transcription PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.