Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Sep:196:106045.
doi: 10.1016/j.clineuro.2020.106045. Epub 2020 Jun 25.

COVID-19 and generalized Myasthenia Gravis exacerbation: A case report

Shivangi Singh  1 , Raghav Govindarajan  2
Affiliations
Case Reports

COVID-19 and generalized Myasthenia Gravis exacerbation: A case report

Shivangi Singh et al. Clin Neurol Neurosurg. 2020 Sep.

Abstract

  1. •

    MG treatment in the context of COVID-19 should be tailored to the patient.

  2. •

    Patient’s respiratory status should be closely monitored.

  3. •

    Concomitant COVID-19 and MG has a variable response to treatment.

Keywords: Covid-19; Exacerbation; Myasthenia Gravis; Neuromuscular; SARS CoV2.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
A 36-year old female with a history of generalized Myasthenia Gravis presented with worsening muscle weakness and shortness of breath. On evaluation, she was also found to be positive for SARS COV-2. She was hospitalized and treated with Plasma Exchange with her home dose of Mycophenolate Mofetil continued. Her respiratory status worsened three days after admission, showing bilateral ground glass opacities as seen in the CT chest below. Patient was intubated for 14 days before being discharged to home.
See this image and copyright information in PMC

References

    1. Sanders D.B. International consensus guidance for management of myasthenia gravis: executive summary. Neurology. 2016;87(4):419–425. - PMC - PubMed
    1. Jacob S. Guidance for the management of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) during the COVID-19 pandemic. J. Neurol. Sci. 2020;412 p. 116803. - PMC - PubMed
    1. Centers for Disease Control; 2020. Symptoms of Coronavirus.https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html Updated March 20, 2020. Accessed May 4, 2020, website.
    1. Anand P. COVID-19 in patients with myasthenia gravis. Muscle Nerve. 2020 - PMC - PubMed
    1. Solé G. Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases Network. Rev. Neurol. (Paris) 2020;176(6):507–515. - PMC - PubMed

Publication types

MeSH terms