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Review
. 2020 Jul 3;12(7):1776.
doi: 10.3390/cancers12071776.

Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Justine N van der Beek  1   2 , James I Geller  3 , Ronald R de Krijger  1   4 , Norbert Graf  5 , Kathy Pritchard-Jones  6 , Jarno Drost  1   7 , Arnauld C Verschuur  8 , Dermot Murphy  9 , Satyajit Ray  9 , Filippo Spreafico  10 , Kristina Dzhuma  6 , Annemieke S Littooij  1   2 , Barbara Selle  11 , Godelieve A M Tytgat  1 , Marry M van den Heuvel-Eibrink  1
Affiliations
Review

Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Justine N van der Beek et al. Cancers (Basel). .

Abstract

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.

Keywords: outcome; pediatric; renal cell carcinoma; survival; treatment.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart. ᵜ These articles were used for additional results and information, if applicable.
See this image and copyright information in PMC

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