Pharmacologic modulation of acute ocular inflammation. I. Adenosine
- PMID: 3263602
- DOI: 10.1159/000266646
Pharmacologic modulation of acute ocular inflammation. I. Adenosine
Abstract
Modulation of signal transduction at the surface of inflammatory cells appears to influence acute inflammation. Adenosine, a well-known chemical messenger, inhibits the production of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal 's' antigen, treatment with adenosine produced a marked reduction in the expected inflammation.
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