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. 1988;20(4):220-6.
doi: 10.1159/000266646.

Pharmacologic modulation of acute ocular inflammation. I. Adenosine

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Pharmacologic modulation of acute ocular inflammation. I. Adenosine

G E Marak Jr et al. Ophthalmic Res. 1988.

Abstract

Modulation of signal transduction at the surface of inflammatory cells appears to influence acute inflammation. Adenosine, a well-known chemical messenger, inhibits the production of superoxide by stimulated neutrophils. In experimental allergic uveitis induced by sensitization with retinal 's' antigen, treatment with adenosine produced a marked reduction in the expected inflammation.

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