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Case Reports
. 2020 Oct;59(5):102866.
doi: 10.1016/j.transci.2020.102866. Epub 2020 Jul 1.

First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia

Magdalena Figlerowicz  1 , Anna Mania  2 , Karol Lubarski  2 , Zuzanna Lewandowska  2 , Wojciech Służewski  2 , Katarzyna Derwich  3 , Jacek Wachowiak  3 , Katarzyna Mazur-Melewska  2
Affiliations
Case Reports

First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia

Magdalena Figlerowicz et al. Transfus Apher Sci. 2020 Oct.

Abstract

We present the case of a six-year-old girl with severe COVID-19, in whom SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion. Children show a variable clinical course of COVID-19, from asymptomatic to critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic anemia remains unclear. At the beginning of the disease, we used antiviral drugs and immune modulators as therapy but without any positive results. After providing a transfusion of convalescent plasma, the elimination of SARS-CoV-2 was observed. We did not observe any adverse events of this treatment. The girl still has a diagnosis of aplastic anemia and requires specialist therapy.

Keywords: Children; Convalescent plasma; Pancytopenia; SARS-CoV-2; Transfusion.

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Conflict of interest statement

None.

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