Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jun 8:17:14.
doi: 10.25259/CytoJournal_6_2020. eCollection 2020.

Cytomorphological diagnosis of rapidly growing, hard, non-tender thyroid lesion

Affiliations

Cytomorphological diagnosis of rapidly growing, hard, non-tender thyroid lesion

Gaurav Singla et al. Cytojournal. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1:
Figure 1:
(a) Follicular neoplasm showing presence of repetitive prominent microfollicular pattern in a colloid free background (Giemsa, ×40), (b) medullary carcinoma small cell variant showing singly scattered cells with stippled chromatin in a background of magenta-colored amyloid (Giemsa, ×40), (c) papillary carcinoma showing a cellular smear forming syncytial aggregates and sheets focally with a distinct anatomical border and scanty viscous colloid (depicted by black arrow) also known as chewing gum colloid can be seen (Giemsa, ×10), (d) large, oval, and pale nuclei seen with pale powdered chromatin and presence of intranuclear cytoplasmic inclusion (depicted by black arrow) best appreciated in Pap stain (Papanicolaou, ×40).
Figure 2:
Figure 2:
(a) Highly cellular smear with a necrotic background (Giemsa, ×10), (b) giant mononuclear cells present with multilobated nuclei, irregular nuclear membrane, and coarsely clumped chromatin (Giemsa, ×40), (c) multinucleated cells (depicted by black arrow) present along with presence of necrosis (as depicted by orange arrow) (Giemsa, ×40), (d) abnormal mitosis (depicted by black arrow) can be appreciated in a background of highly pleomorphic malignant cells (Giemsa, ×40).

Similar articles

References

    1. Mehdi G, Maheshwari V, Ansari HA, Sadaf L, Khan MA. FNAC diagnosis of medullary carcinoma thyroid: A report of three cases with review of literature. J Cytol. 2010;27:66–8. doi: 10.4103/0970-9371.70745. - DOI - PMC - PubMed
    1. Nagpal R, Kaushal M, Kumar S. Cytological diagnosis of an uncommon high grade malignant thyroid tumour: A case report. J Clin Diagn Res. 2017;11:ED03–5. doi: 10.7860/JCDR/2017/28531.10132. - DOI - PMC - PubMed
    1. Ragazzi M, Ciarrocchi A, Sancisi V, Gandolfi G, Bisagni A, Piana S. Update on anaplastic thyroid carcinoma: Morphological, molecular, and genetic features of the most aggressive thyroid cancer. Int J Endocrinol. 2014;2014:790834. doi: 10.1155/2014/790834. - DOI - PMC - PubMed
    1. Dwipayana MP, Yogi P, Semadi S, Wirawan S, Widiana K. Diagnosis and management of an anaplastic thyroid cancer: Case report. Biomed Pharmacol J. 2017;10:1369–77. doi: 10.13005/bpj/1241. - DOI
    1. Chiacchio S, Lorenzoni A, Boni G, Rubello D, Elisei R, Mariani G. Anaplastic thyroid cancer: Prevalence, diagnosis and treatment. Minerva Endocrinol. 2008;33:341–57. - PubMed

LinkOut - more resources