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Case Reports
. 2020 Jun 29;15(8):1394-1397.
doi: 10.1016/j.radcr.2020.06.013. eCollection 2020 Aug.

Gallbladder schistosomiasis - a rare presentation as gallbladder polyp: a case report

Pragya Gautam Ghimire  1 , Prasanna Ghimire  2
Affiliations
Case Reports

Gallbladder schistosomiasis - a rare presentation as gallbladder polyp: a case report

Pragya Gautam Ghimire et al. Radiol Case Rep. .

Abstract

Background: Schistosomiasis is a neglected tropical disease second to malaria in prevalence with significant morbidity and mortality. Although, Schistosomiasis can affect multiple organs, gallbladder involvement is very rarely reported. We present a case of isolated gallbladder schistosomiasis in a 20-year-old female presenting as gallbladder polyp radiologically and also correlated the histopathological findings which to our knowledge has never been reported in the English literature. A high index of suspicion should be made for considering Schistosomiasis when an individual hailing from endemic region presents with gallbladder pathologies.

Keywords: Gallbladder; Histopathology; S. japonicum, Schistosoma japonicum; Schistosomiasis; Tropical.

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Figures

Fig. 1 –
Fig. 1
(a) Axial ultrasound image demonstrates diffusely thickened gallbladder wall and an echogenic polypoidal lesion with no posterior acoustic shadowing at the fundal region of gallbladder. (b) Zoomed ultrasound image demonstrates gallbladder polyp. No foci of calcification or cystic areas are noted.
Fig. 2 –
Fig. 2
(a) Photomicrograph showing numerous “egg –granulomas” embedded in the lamina propria and muscular layer (original magnification × 40) H & E stain. (b) Photomicrograph showing wall of gallbladder with papillary infoldings lined by tall columnar epithelium with focal areas of antral metaplasia. Egg-granuloma is also noted in the center (original magnification × 40), H & E stain. (c) Photomicrograph showing two oval transparent membranous sheath resembling shell of parasitic eggs surrounded by granulomatous reaction “pseudotubercle.” Multinucleated foreign body giant cells are also noted (Original magnification × 100), H & E stain. (d) Photomicrograph shows gallbladder wall with replacement fibrosis and mild lymphocytic infiltrate in the lamina and muscular layer. The perimuscular layer appears fibrosed with dilated and congested vasculature with one pseudotubercle (blue arrow), (Original magnification × 25), H & E stain. (Color version available online.)
See this image and copyright information in PMC

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