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. 2020 Jun 24:56:125-127.
doi: 10.1016/j.amsu.2020.06.018. eCollection 2020 Aug.

A severe refractory COVID-19 patient responding to convalescent plasma; A case series

Hadi Mohammed Abdullah  1 , Hersh H Hama-Ali  2 , Sabah Nasraddin Ahmed  3 , Kosar Muhammad Ali  4 , Kamaran Amin Karadakhy  4 , Safeen Othman Mahmood  4 , Zana Hameed Mahmood  5 , Karmand Qadir Hamad Amin  2 , Peshnyar Muhammad Atta  5 , Bryar Ezadeen Nuradeen  6 , Shvan H Mohammed  7 , Rawezh Q Salih  7   8 , Hiwa O Baba  7   8 , Fahmi H Kakamad  4   7   8
Affiliations

A severe refractory COVID-19 patient responding to convalescent plasma; A case series

Hadi Mohammed Abdullah et al. Ann Med Surg (Lond). .

Abstract

Introduction: Although some medicines are under research, currently, no specific antiviral drug has been approved to target 2019 novel coronavirus. In this report two severe cases of 2019 novel coronavirus disease (COVID-19) patients have been described who received convalescent plasma (CP).

Case report: Two male cases (a 46-year-old and a 56-year-old) after being diagnosed with severe COVID-19, they deteriorated despite supportive care and antiviral therapy. They started to improve with CP infusion both clinically and radiologically. Finally they were discharged in a very well condition with negative virology tests.

Conclusion: CP might be an effective therapy for severe COVID-19 patients.

Keywords: COVID-19; Convalescent plasma; Coronavirus; SARS-CoV-2.

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Conflict of interest statement

None to be declared.

Figures

Fig. 1
Fig. 1
CT-scan (coronal section) showing diffuse ground glass opacity with multiple areas of consolidation.
Fig. 2
Fig. 2
Chest CT-scan (axial section) of the second case showing bilateral diffuse ground glass opacities with consolidation.
See this image and copyright information in PMC

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