The use of radiological imaging alongside reverse transcriptase PCR in diagnosing novel coronavirus disease 2019: a narrative review
- PMID: 32638613
- PMCID: PMC7341952
- DOI: 10.2217/fmb-2020-0098
The use of radiological imaging alongside reverse transcriptase PCR in diagnosing novel coronavirus disease 2019: a narrative review
Abstract
The diagnosis of novel coronavirus disease 2019 (COVID-19) has been a challenge in many countries due to nonspecific symptoms and variable incubation period. The current reference test is reverse transcriptase PCR. Many studies have reported high sensitivities of CT scans and suggested that they can be used in the diagnosis of COVID-19 alongside reverse transcriptase PCR. The current data about CT scans are highly variable and incoherent. Therefore, new multicentric studies in different countries are needed to better understand the role of CT scans in COVID-19 diagnosis. In this report, we will discuss the clinical relevance of each test and the current Centers for Disease Control and Prevention and American College of Radiology recommendations regarding the use of imaging in the diagnosis of COVID-19.
Keywords: COVID-19; CT scan; chest x-ray; diagnostic radiology; virology.
Comment on
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Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia.Radiology. 2020 Apr;295(1):210-217. doi: 10.1148/radiol.2020200274. Epub 2020 Feb 6. Radiology. 2020. PMID: 32027573 Free PMC article.
References
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- Ai T, Yang Z, Hou H. et al. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology (2020) (Epub ahead of print). - PMC - PubMed
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• Discusses the importance of background chest computed tomography (CT) being used for diagnosis of novel coronavirus disease 2019 (COVID-19) alongside reverse transcriptase PCR. In addition, this study determines the sensitivity and specificity of CT scans compared with reverse transcriptase PCR in COVID-19 patients.
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- World Health Organisation. WHO Director-General's opening remarks at the media briefing on COVID-19. (2020). http://www.who.int/dg/speeches/detail/who-director-general-s-opening-rem...
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- World Health Organisation. Coronavirus disease (COVID-19) pandemic. (2020. ). http://www.who.int/emergencies/diseases/novel-coronavirus-2019
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