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Case Reports
. 2020 Aug;39(8):e206-e207.
doi: 10.1097/INF.0000000000002804.

Pediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection

Tslil Regev  1 , Maayan Antebi  1 , Danny Eytan  2   3 , Yael Shachor-Meyouhas  4 , Anat Ilivitzki  1 , Yonatan Butbul Aviel  3   5   6 , Josef Ben-Ari  2
Affiliations
Case Reports

Pediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection

Tslil Regev et al. Pediatr Infect Dis J. 2020 Aug.

Abstract

Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.

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References

    1. World Health Organization. Novel coronavirus-China. Available at: https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china. Accessed May 5, 2020.
    1. Lu R, Zhao X, Li J, et al.Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395:565–574.
    1. Dong Y, Mo X, Hu Y, et al.Epidemiology of COVID-19 among children in China. Pediatrics. 2020.
    1. Parri N, Lenge MChildren with Covid-19 in pediatric emergency departments in Italy. N Engl J Med. 2020. Epub ahead of print.
    1. Riphagen S, Gomez X, Gonzalez-Martinez C, et al.Hyperinflammatory shock in children during COVID-19 pandemic [correspondence]. Lancet. 2020;395:1607–1608.

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