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Review
. 2020 Jul;35(3):285-289.
doi: 10.1007/s12291-020-00906-5. Epub 2020 Jun 27.

COVID-19: Current Trends in Invitro Diagnostics

R Arun Krishnan  1 , Rhema Elizabeth Thomas  1 , Ajaikumar Sukumaran  1 , Jofy K Paul  1 , D M Vasudevan  1
Affiliations
Review

COVID-19: Current Trends in Invitro Diagnostics

R Arun Krishnan et al. Indian J Clin Biochem. 2020 Jul.

Abstract

The novel coronavirus SARS-CoV-2 is the seventh known species of coronavirus, infectious to human beings. The pandemic COVID-19 spread all over the world with an unprecedented spreading rate after its first appearance in Wuhan, China. As a novel viral disease there in no antiviral treatment or vaccine for the COVID-19. At present, the early detection and the quarantine of infected patients are the ways to stop the spreading of the disease. This review will discuss about the current invitro diagnostic methods used worldwide for the early and accurate diagnosis of COVID-19. Currently the nucleic acid based polymerase chain reaction is used as the reliable diagnostic platform and antigen/antibody detection immunoassays are playing the role of screening tests for early detection and prognosis in COVID-19 treatment.

Keywords: CLIA; ELISA; Lateral flow immunoassay; Loop mediated isothermal amplification; Reverse transcriptase PCR; SARS-CoV-2.

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Conflict of interest statement

Conflict of interestAll authors declare that there is no conflict of interest.

Figures

Fig. 1
Fig. 1
Schematic diagram of SARS-COV-2
See this image and copyright information in PMC

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