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. 2020 Jun 29;10(3):e2020063.
doi: 10.5826/dpc.1003a63. eCollection 2020 Jul.

Dermoscopy of Congenital Langerhans Cell Histiocytosis

Ramon Pigem  1 , Ariann Dyer  1 , Sebastian Podlipnik  1 , Cristina Carrera  1 , Susana Puig  1 , Juan Ferrando  1
Affiliations

Dermoscopy of Congenital Langerhans Cell Histiocytosis

Ramon Pigem et al. Dermatol Pract Concept. .
No abstract available

Keywords: Langerhans cell; dermoscopy; histiocytosis; solar eclipse.

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Conflict of interest statement

Competing interests: The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Dermoscopic examination of a lesion in the fully developed stage. The dark pigmentation in the center and the violaceous vessels on the periphery resemble a solar eclipse over a starry sky. Note the burgundy color of the vessels.
Figure 2
Figure 2
Dermoscopic examination of 2 different lesions. (A) Lesion in the early evolutionary stage with multiple violaceous lacunae and mild brown pigmentation. (B) Different lesion in the late regressive stage with central scar surrounded by whitish streaks and an eccentric focus of residual pigmentation.
Figure 3
Figure 3
H&E-stained biopsy showing a dense dermal infiltrate of large histiocytes with pale cytoplasm and ectatic vessels in the dermis. Original magnification ×40.
Figure 4
Figure 4
(A) Electron microscopy shows Birbeck and vermiform bodies. (B) Large histiocytes with reniform nuclei were also observed.
See this image and copyright information in PMC

References

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