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Book

Dialysis Disequilibrium Syndrome

Binita Bhandari  1 , Saketram Komanduri  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

Dialysis Disequilibrium Syndrome

Binita Bhandari et al.
Free Books & Documents

Excerpt

Dialysis disequilibrium syndrome (DDS) refers to an array of neurological manifestations seen during or following dialysis, primarily after the new initiation of dialysis. However, it can also be seen in chronic dialysis patients who miss their regular dialysis treatments. This syndrome is thought to arise from fluid shifts during hemodialysis, causing cerebral edema and a wide variety of neurological symptoms. In continuous renal replacement therapies (CRRT), where fluid shift is limited, dialysis disequilibrium syndrome is rarely reported.

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Conflict of interest statement

Disclosure: Binita Bhandari declares no relevant financial relationships with ineligible companies.

Disclosure: Saketram Komanduri declares no relevant financial relationships with ineligible companies.

References

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    1. Arieff AI. Dialysis disequilibrium syndrome: current concepts on pathogenesis and prevention. Kidney Int. 1994 Mar;45(3):629-35. - PubMed
    1. Tuchman S, Khademian ZP, Mistry K. Dialysis disequilibrium syndrome occurring during continuous renal replacement therapy. Clin Kidney J. 2013 Oct;6(5):526-9. - PMC - PubMed
    1. Bagshaw SM, Peets AD, Hameed M, Boiteau PJ, Laupland KB, Doig CJ. Dialysis Disequilibrium Syndrome: brain death following hemodialysis for metabolic acidosis and acute renal failure--a case report. BMC Nephrol. 2004 Aug 19;5:9. - PMC - PubMed
    1. Zepeda-Orozco D, Quigley R. Dialysis disequilibrium syndrome. Pediatr Nephrol. 2012 Dec;27(12):2205-11. - PMC - PubMed

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