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Book

Hepatocellular Carcinoma

Kwabena O. Asafo-Agyei  1 , Hrishikesh Samant  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Hepatocellular Carcinoma

Kwabena O. Asafo-Agyei et al.
Free Books & Documents

Excerpt

Hepatocellular carcinoma (HCC) is a primary tumor of the liver and constitutes more than 90% of the primary tumor of the liver. Hepatocellular carcinoma occurs in approximately 85% of patients diagnosed with cirrhosis. HCC is now the fifth most common cause of cancer worldwide. The second leading cause of cancer death after lung cancer in men is HCC. Five-year survival of HCC is 18% and second to pancreatic cancer. Significant risk factors for hepatocellular carcinoma include viral hepatitis (hepatitis B and hepatitis C), alcoholic liver disease, and non-alcoholic liver steatohepatitis/non-alcoholic fatty liver disease. HCC occurs in 80%-90% of patients with cirrhosis. The annual incidence of HCC in patients with cirrhosis is 2-4%.

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Conflict of interest statement

Disclosure: Kwabena Asafo-Agyei declares no relevant financial relationships with ineligible companies.

Disclosure: Hrishikesh Samant declares no relevant financial relationships with ineligible companies.

References

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