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Book

Oligodendroglioma

Craig A. Tork  1 , Walter A. Hall  2 , Christopher Atkinson  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Oligodendroglioma

Craig A. Tork et al.
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Excerpt

Oligodendroglioma (OG) is a diffusely infiltrating glioma representing approximately 5% of all primary intracranial tumors. These tumors often involve the cortical gray and the white matter and are most commonly located in the frontal lobes. Historically, the OG was diagnosed by the histological appearance of the tumor. However, in 2016, the World Health Organization (WHO) changed the criteria for classifying central nervous system (CNS) tumors to include a phenotypic and genotypic analysis. OGs are generally low-grade WHO grade II neoplasms that are slow-growing tumors and have a favorable response to treatment compared to other gliomas. The grade III anaplastic OG is a highly malignant form of the tumor that has an unfavorable prognosis and may occur de novo or as a malignant transformation from the lower grade OG.

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Conflict of interest statement

Disclosure: Craig Tork declares no relevant financial relationships with ineligible companies.

Disclosure: Walter Hall declares no relevant financial relationships with ineligible companies.

Disclosure: Christopher Atkinson declares no relevant financial relationships with ineligible companies.

References

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