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Comment
. 2020 Jul 8;28(1):1-2.
doi: 10.1016/j.chom.2020.06.016.

Not Your Typical Anti-CRISPR

Welkin E Johnson  1
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Free article
Comment

Not Your Typical Anti-CRISPR

Welkin E Johnson. Cell Host Microbe. .
Free article

Abstract

In this issue of Cell Host & Microbe, two papers by Osuna et al. describe the characterization of AcrIIA1, an anti-CRISPR protein distributed widely among Listeria phages. AcrIIA1 functions as an anti-CRISPR and as a dynamic repressor of acr loci, suggesting it may play an important role in lysogeny.

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  • Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes.
    Osuna BA, Karambelkar S, Mahendra C, Christie KA, Garcia B, Davidson AR, Kleinstiver BP, Kilcher S, Bondy-Denomy J. Osuna BA, et al. Cell Host Microbe. 2020 Jul 8;28(1):31-40.e9. doi: 10.1016/j.chom.2020.04.001. Epub 2020 Apr 22. Cell Host Microbe. 2020. PMID: 32325050 Free PMC article.

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