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Editorial
. 2020 Jun;8(12):778.
doi: 10.21037/atm.2020.02.68.

Is pembrolizumab monotherapy the optimal treatment for elderly patients with PD-L1 positive advanced non-small cell lung cancer?

Affiliations
Editorial

Is pembrolizumab monotherapy the optimal treatment for elderly patients with PD-L1 positive advanced non-small cell lung cancer?

Fiona Mienko et al. Ann Transl Med. 2020 Jun.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.02.68). BH has received research funding from Merck, Astra-Zeneca, Boehringer-Ingelheim, Pfizer, Novartis, GSK, AbbVie, Mirati, Eli-Lilly, Takeda and BMS and consulting fees from Foundation Medicine, Guardant Health 360, Eli-Lilly, Novartis, Pfizer, BoehringerIngelheim, Astra-Zeneca, Spectrum, BMS, Merck, Genentech and Takeda. The other authors have no conflicts of interest to declare.

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References

    1. Maione P, Rossi A, Sacco PC, et al. Treating advanced non-small cell lung cancer in the elderly. Ther Adv Med Oncol 2010;2:251-60. 10.1177/1758834010366707 - DOI - PMC - PubMed
    1. Bravo-Iñiguez C, Perez Martinez M, Armstrong KW, et al. Surgical resection of lung cancer in the elderly. Thorac Surg Clin 2014;24:371-81. 10.1016/j.thorsurg.2014.07.001 - DOI - PubMed
    1. O'Connor JM, Fessele KL, Steiner J, et al. Speed of adoption of immune checkpoint inhibitors of programmed cell death 1 protein and comparison of patient ages in clinical practice vs pivotal clinical trials. JAMA Oncol 2018;4:e180798. 10.1001/jamaoncol.2018.0798 - DOI - PMC - PubMed
    1. Herbst RS, Baas P, Kim DW, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 2016;387:1540-50. 10.1016/S0140-6736(15)01281-7 - DOI - PubMed
    1. Reck M, Rodríguez-Abreu D, Robinson AG, et al. Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer. N Engl J Med 2016;375:1823-33. 10.1056/NEJMoa1606774 - DOI - PubMed