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. 2022 Jan 7;74(1):127-132.
doi: 10.1093/cid/ciaa964.

Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

Carolina Garcia-Vidal  1 , Estela Moreno-García  1 , Marta Hernández-Meneses  1 , Pedro Puerta-Alcalde  1 , Mariana Chumbita  1 , Nicole Garcia-Pouton  1 , Laura Linares  1 , Verónica Rico  1 , Celia Cardozo  1 , José Antonio Martínez  1 , Felipe García  1 , Josep Mensa  1 , Pedro Castro  2 , José María Nicolás  2 , José Muñoz  3 , David Vidal  4 , Alex Soriano  1 ; COVID19-Researchers
Collaborators, Affiliations

Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

Carolina Garcia-Vidal et al. Clin Infect Dis. .

Abstract

Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03-.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.

Keywords: COVID-19; patterns; personalized therapy; pneumonia.

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