Review
doi: 10.1007/s40257-020-00532-0.
Alternative Clinical Indications of Botulinum Toxin
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- PMID: 32651806
- DOI: 10.1007/s40257-020-00532-0
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Review
Alternative Clinical Indications of Botulinum Toxin
Am J Clin Dermatol.
2020 Dec.
Abstract
Botulinum toxin type A (BoNTA) is a powerful neurotoxin that inhibits acetylcholine release from presynaptic vesicles. The potency and safety profile of BoNTA grant the toxin vast therapeutic potential. It has been used off-label for a variety of dermatologic conditions. This review aims to analyze published literature regarding the benefits and risks of the off-label use of BoNTA beyond facial lines, including eccrine hidrocystomas, enlarged pores, keloids and hypertrophic scars, hidradenitis suppurativa, hyperhidrosis, masseter muscle hypertrophy, and salivary gland hypertrophy, among others. A MEDLINE search from January 2000 to December 2019 was conducted on the off-label uses of botulinum toxin in dermatology.
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