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Review
. 2020 Sep:35:43-49.
doi: 10.1016/j.prrv.2020.06.010. Epub 2020 Jun 18.

Vaccines for COVID-19: The current state of play

Archana Koirala  1 , Ye Jin Joo  2 , Ameneh Khatami  3 , Clayton Chiu  4 , Philip N Britton  5
Affiliations
Review

Vaccines for COVID-19: The current state of play

Archana Koirala et al. Paediatr Respir Rev. 2020 Sep.

Abstract

There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 - the virus that causes COVID-19 - currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead.

Keywords: Covid 19; Human trials; Timeline; Vaccines.

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Figures

Fig. 1
Fig. 1
Schematic of the structure of SARS-CoV2. (Adapted from Lee, C-Y et al, Frontiers in Immunology, 2020).
See this image and copyright information in PMC

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