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. 2020 Nov;47(11):1403-1415.
doi: 10.1111/jcpe.13346. Epub 2020 Sep 9.

Aesthetic-And patient-related outcomes following root coverage procedures: A systematic review and network meta-analysis

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Free article

Aesthetic-And patient-related outcomes following root coverage procedures: A systematic review and network meta-analysis

Francesco Cairo et al. J Clin Periodontol. 2020 Nov.
Free article

Abstract

Background: Aim of this systematic review (SR) of randomized controlled trials (RCTs) was to evaluate effect of different flap designs and graft materials for root coverage, in terms of aesthetics, patient satisfaction and self-reported morbidity (post-operative pain/discomfort).

Material and methods: A comprehensive literature search was performed. A mixed-modelling approach to network meta-analysis was utilized to formulate direct and indirect comparisons among treatments for Root Coverage Esthetic Score (RES), with its individual components, and for subjective patient-reported satisfaction and post-operative pain/discomfort (visual analogue scale (VAS) of 100).

Results: Twenty-six RCTs with a total of 867 treated patients (1708 recessions) were included. Coronally Advanced Flap (CAF) + Connective Tissue Graft (CTG) (0.74 (95% CI [0.24, 1.26], p = .005)), Tunnel (TUN) + CTG (0.84 (95% CI [0.15, 1.53]), p = .01) and CAF + Graft substitutes (GS) (0.55 (95% CI [0.006, 1.094], p = .04)) were significantly associated with higher RES than CAF. No significant difference between CAF + CTG and TUN + CTG was detected (0.09 (95% CI [-0.54, 0.72], p = .77)). Addition of CTG resulted in less natural tissue texture (-0.21 (95% CI [-0.34, -0.08]), p = .003) and gingival colour (-0.06 (95% CI [-0.12, -0.03], p = .03)) than CAF. CTG techniques were associated with increased morbidity.

Conclusions: Connective tissue graft procedures showed highest overall aesthetic performance for root coverage, although graft integration might impair soft tissue colour and appearance. Additionally, CTG-based techniques were also correlated with a greater patient satisfaction and morbidity.

Keywords: aesthetics; connective tissue graft; coronally advanced flap; gingival recession; meta-analysis.

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References

REFERENCES

    1. Ahmedbeyli, C., Dirikan Ipci, S., Cakar, G., Yilmaz, S., & Chambrone, L. (2019). Coronally advanced flap and envelope type of flap plus acellular dermal matrix graft for the treatment of thin phenotype multiple recession defects. A randomized clinical trial. Journal of Clinical Periodontology, 46, 1024-1029. https://doi.org/10.1111/jcpe.13174
    1. Ahmedbeyli, C., Ipci, S. D., Cakar, G., Kuru, B. E., & Yilmaz, S. (2014). Clinical evaluation of coronally advanced flap with or without acellular dermal matrix graft on complete defect coverage for the treatment of multiple gingival recessions with thin tissue biotype. Journal of Clinical Periodontology, 41, 303-310. https://doi.org/10.1111/jcpe.12211
    1. Aichelmann-Reidy, M. E., Yukna, R. A., Evans, G. H., Nasr, H. F., & Mayer, E. T. (2001). Clinical evaluation of acellular allograft dermis for the treatment of human gingival recession. Journal of Periodontology, 72, 998-1005. https://doi.org/10.1902/jop.2001.72.8.998
    1. Aydinyurt, H. S., Tekin, Y., & Ertugrul, A. S. (2019). The effect of enamel matrix derivatives on root coverage: A 12-month follow-up of a randomized clinical trial. Brazilian Oral Research, 33, e006. https://doi.org/10.1590/1807-3107bor-2019.vol33.0006
    1. Azaripour, A., Kissinger, M., Farina, V. S., Van Noorden, C. J., Gerhold-Ay, A., Willershausen, B., & Cortellini, P. (2016). Root coverage with connective tissue graft associated with coronally advanced flap or tunnel technique: A randomized, double-blind, mono-centre clinical trial. Journal of Clinical Periodontology, 43, 1142-1150. https://doi.org/10.1111/jcpe.12627

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