doi: 10.1080/10286020.2020.1791099.
Epub 2020 Jul 11.
Chemical constituent with cytotoxicity from Sterculia diversifolia
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- PMID: 32654513
- DOI: 10.1080/10286020.2020.1791099
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Chemical constituent with cytotoxicity from Sterculia diversifolia
J Asian Nat Prod Res.
2021 Sep.
Abstract
One new coumarin (stercularin), along with eleven known compounds, was isolated for the first time from ethyl acetate fraction of Sterculia diversifolia. The structures of isolated compounds were characterized by spectroscopic techniques such as EIMS, 1H-NMR and 13C-NMR. Compound 1 showed significant cytotoxicity by brine shrimp lethality assay (LD50: 8.00 μg/ml) and PC-3 cell lines protocol (IC50: 3.92 ± 0.20 μg/ml), respectively.
Keywords: MESD; Sterculia diversifolia; Sterculiaceae; coumarin; cytotoxicity; spectroscopy.
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