Targeting microglia to mitigate perioperative neurocognitive disorders

Affiliations

¹ Department of Physiology, University of Toronto, Toronto, ON, Canada.
² Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
³ Department of Physiology, University of Toronto, Toronto, ON, Canada; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada; Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Electronic address: beverley.orser@utoronto.ca.

Free article

Editorial

Dian-Shi Wang et al. Br J Anaesth. 2020 Sep.

Free article

. 2020 Sep;125(3):229-232.

doi: 10.1016/j.bja.2020.06.027. Epub 2020 Jul 9.

¹ Department of Physiology, University of Toronto, Toronto, ON, Canada.
² Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
³ Department of Physiology, University of Toronto, Toronto, ON, Canada; Department of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada; Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Electronic address: beverley.orser@utoronto.ca.

No abstract available

Keywords: astrocyte; microglia; neuroinflammation; neurone; perioperative neurocognitive disorders; surgery.

Comment on

Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice.
Lai IK, Valdearcos M, Morioka K, Saxena S, Feng X, Li R, Uchida Y, Lijun A, Li W, Pan J, Koliwad S, Marcucio R, Wulff H, Maze M. Lai IK, et al. Br J Anaesth. 2020 Sep;125(3):298-307. doi: 10.1016/j.bja.2020.05.018. Epub 2020 Jul 2. Br J Anaesth. 2020. PMID: 32624183 Free PMC article.