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Case Reports
. 2020 Sep;158(3):538-546.
doi: 10.1016/j.ygyno.2020.06.160. Epub 2020 Jul 10.

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Comprehensive management of a newly diagnosed young adult

Joseph G Pressey  1 , Christopher E Dandoy  2 , Luke E Pater  3 , Julie Sroga Rios  4 , Rebecca Sisson  5 , Roshni Dasgupta  6 , Sara Szabo  7
Affiliations
Case Reports

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Comprehensive management of a newly diagnosed young adult

Joseph G Pressey et al. Gynecol Oncol. 2020 Sep.

Abstract

SCCOHT is an aggressive malignancy linked to alterations of SMARCA4. We describe the diagnosis and therapy of a 32 year old who received multi-agent chemotherapy and underwent a second look operation with HIPEC followed by high-dose chemotherapy with stem cell transplant. Supportive care, oncofertility, and genetic counseling are described.

Keywords: AYA; Ovarian; Rhabdoid; SCCOHT; SMARCA4; Transplant.

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Declaration of competing interest None.

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