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. 2020 Jul 31;38(35):5564-5568.
doi: 10.1016/j.vaccine.2020.06.083. Epub 2020 Jul 3.

Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality

Ahmed Osama El-Gendy  1 , Haitham Saeed  2 , Ahmed M A Ali  3 , Hossam M Zawbaa  4 , Dina Gomaa  5 , Hadeer S Harb  2 , Yasmin M Madney  2 , Hasnaa Osama  2 , Mona A Abdelrahman  2 , Mohamed E A Abdelrahim  6
Affiliations

Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality

Ahmed Osama El-Gendy et al. Vaccine. .

Abstract

COVID-19 is affecting different countries all over the world with great variation in infection rate and death ratio. Some reports suggested a relation between the Bacillus Calmette-Guérin (BCG) vaccine and the malaria treatment to the prevention of SARS-CoV-2 infection. Some reports related infant's lower susceptibility to the COVID-19. Some other reports a higher risk in males compared to females in such COVID-19 pandemic. Also, some other reports claimed the possible use of chloroquine and hydroxychloroquine as prophylactic in such a pandemic. The present commentary is to discuss the possible relation between those factors and SARS-CoV-2 infection.

Keywords: Age; Antimalarial; BCG; COVID 19; Gender.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
A. Map displaying BCG-vaccination policy by country (adopted from [16]); B. Number of confirmed COVID-19 cases and death cases in certain countries; C. The-estimate of world malaria burden (adopted from [57]); D Number of confirmed COVID-19 cases and death cases for countries receiving antimalarial treatment.
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