Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide
- PMID: 326565
- DOI: 10.1002/eji.1830070517
Genetic defect in responsiveness to the B cell mitogen lipopolysaccharide
Abstract
Splenic B cells C57BL/10ScCr mice fail to respond to the mitogenic principle of lipopolysaccharide (LPS), and do not express a serologically defined "LPS receptor". In contrast, polyclonal B cell responses to both purified protein derivative of tuberculin and lipoprotein are conserved.
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