Editorial: early TIPSS in patients with cirrhosis and acute variceal bleeding-the plot thickens!

Faisal Khan¹, Dhiraj Tripathi^{2

3

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Affiliations

¹ University Hospital Coventry & Warwickshire, Coventry, UK.
² Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
³ NIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham, NHS Foundation Trust and University of Birmingham, Birmingham, UK.
⁴ Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

Editorial

Faisal Khan et al. Aliment Pharmacol Ther. 2020 Aug.

. 2020 Aug;52(3):551-554.

doi: 10.1111/apt.15904.

Faisal Khan¹, Dhiraj Tripathi^{2

3

4}

¹ University Hospital Coventry & Warwickshire, Coventry, UK.
² Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
³ NIHR Birmingham Biomedical Research Centre, University Hospitals Birmingham, NHS Foundation Trust and University of Birmingham, Birmingham, UK.
⁴ Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.

No abstract available

Comment on

Randomised clinical trial: standard of care versus early-transjugular intrahepatic porto-systemic shunt (TIPSS) in patients with cirrhosis and oesophageal variceal bleeding.
Dunne PDJ, Sinha R, Stanley AJ, Lachlan N, Ireland H, Shams A, Kasthuri R, Forrest EH, Hayes PC. Dunne PDJ, et al. Aliment Pharmacol Ther. 2020 Jul;52(1):98-106. doi: 10.1111/apt.15797. Epub 2020 May 26. Aliment Pharmacol Ther. 2020. PMID: 32452561 Clinical Trial.

1. Monescillo A, Martinez-Lagares F, Ruiz-del-Arbol L, et al. Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleeding. Hepatology. 2004;40:793-801.
1. García-Pagán JC, Caca K, Bureau C, et al. Early use of TIPS in patients with cirrhosis and variceal bleeding. N Engl J Med. 2010;362:2370-2379.
1. de Franchis R, Baveno VIF. Expanding consensus in portal hypertension: report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension. J Hepatol. 2015;63:743-752.
1. Tripathi D, Stanley AJ, Hayes PC, et al. Transjugular intrahepatic portosystemic stent-shunt in the management of portal hypertension. Gut. 2020;69(7):1173-1192. http://dx.doi.org/10.1136/gutjnl-2019-320221
1. Hernandez-Gea V, Procopet B, Giraldez A, et al. Preemptive-TIPS improves outcome in high-risk variceal bleeding: an observational study. Hepatology. 2019.69(1):285-293.