Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jan;40(1):23-29.
doi: 10.14366/usg.20068. Epub 2020 Jul 3.

Applications of machine learning and deep learning to thyroid imaging: where do we stand?

Affiliations

Applications of machine learning and deep learning to thyroid imaging: where do we stand?

Eun Ju Ha et al. Ultrasonography. 2021 Jan.

Abstract

Ultrasonography (US) is the primary diagnostic tool used to assess the risk of malignancy and to inform decision-making regarding the use of fine-needle aspiration (FNA) and postFNA management in patients with thyroid nodules. However, since US image interpretation is operator-dependent and interobserver variability is moderate to substantial, unnecessary FNA and/or diagnostic surgery are common in practice. Artificial intelligence (AI)-based computeraided diagnosis (CAD) systems have been introduced to help with the accurate and consistent interpretation of US features, ultimately leading to a decrease in unnecessary FNA. This review provides a developmental overview of the AI-based CAD systems currently used for thyroid nodules and describes the future developmental directions of these systems for the personalized and optimized management of thyroid nodules.

Keywords: Artificial intelligence; Computer-aided diagnosis; Neoplasms; Thyroid.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1.
Fig. 1.. History of risk-stratification systems and the development of artificial intelligence (AI)-based computer-aided diagnosis (CAD) systems.
US, ultrasonography.
Fig. 2.
Fig. 2.. Ultrasound (US) image interpretation of a thyroid nodule using a commercialized computer-aided diagnosis (CAD) system (S-Detect Thyroid).
A. A solid hypoechoic nodule with suspicious US features is evident in the right thyroid gland. B. CAD software automatically calculates the mass contours and presents US features on the right side of the screen, and a possible diagnosis as a malignant nodule at the bottom. See the video clip at the following link: https://www.youtube.com/watch?v=Bb2NNpF3zpI.

References

    1. Haugen BR. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: what is new and what has changed? Cancer. 2017;123:372–381. - PubMed
    1. Shin JH, Baek JH, Chung J, Ha EJ, Kim JH, Lee YH, et al. Ultrasonography diagnosis and imaging-based management of thyroid nodules: revised Korean Society of Thyroid Radiology consensus statement and recommendations. Korean J Radiol. 2016;17:370–395. - PMC - PubMed
    1. Ha EJ, Baek JH, Na DG. Risk stratification of thyroid nodules on ultrasonography: current status and perspectives. Thyroid. 2017;27:1463–1468. - PubMed
    1. Choi SH, Kim EK, Kwak JY, Kim MJ, Son EJ. Interobserver and intraobserver variations in ultrasound assessment of thyroid nodules. Thyroid. 2010;20:167–172. - PubMed
    1. Kim HG, Kwak JY, Kim EK, Choi SH, Moon HJ. Man to man training: can it help improve the diagnostic performances and interobserver variabilities of thyroid ultrasonography in residents? Eur J Radiol. 2012;81:e352–e356. - PubMed

LinkOut - more resources