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Review
. 2020 Dec;258(12):2583-2596.
doi: 10.1007/s00417-020-04826-1. Epub 2020 Jul 13.

Paracentral acute middle maculopathy-review of the literature

Nuno Moura-Coelho  1   2   3 , Teresa Gaspar  4   5 , Joana Tavares Ferreira  6   7   8   9 , Marco Dutra-Medeiros  10   11   12   13 , João Paulo Cunha  6   8
Affiliations
Review

Paracentral acute middle maculopathy-review of the literature

Nuno Moura-Coelho et al. Graefes Arch Clin Exp Ophthalmol. 2020 Dec.

Abstract

Paracentral acute middle maculopathy (PAMM) is a recently identified spectral-domain optical coherence tomography (SD-OCT) finding characterized by a hyper-reflective band spanning the inner nuclear layer (INL), which typically evolves to INL atrophy in later stages. Typical clinical features include the sudden onset of one or multiple paracentral scotomas, normal or mild reduction in visual acuity, and a normal fundus appearance or a fundus with a deep grayish lesion. Although its pathophysiology is not yet fully understood, ischemia at the level of the intermediate and deep capillary plexa has been demonstrated to play a major role. Since its first description, an increasing number of publications on PAMM have been published in ophthalmology scientific journals. The purpose of this study is to provide a review of the current literature on PAMM.

Keywords: Deep capillary ischemia; Paracentral acute middle maculopathy; Retinal imaging; Spectral-domain optical coherence tomography, optical coherence tomography angiography.

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References

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