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Comment
. 2020 Jul 13;38(1):25-27.
doi: 10.1016/j.ccell.2020.06.008.

Prostate Cancer 2020: "The Times They Are a'Changing"

Alec Paschalis  1 , Johann S de Bono  2
Affiliations
Free article
Comment

Prostate Cancer 2020: "The Times They Are a'Changing"

Alec Paschalis et al. Cancer Cell. .
Free article

Abstract

Prostate cancer (PC) care is rapidly evolving, with improved treatment options and outcomes. Trials recently published in the New England Journal of Medicine report on an oral lutenizing-hormone-releasing hormone antagonist with superior endocrine and tolerability profiles and positive outcomes for non-metastatic PC with androgen receptor antagonists, respectively.

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Conflict of interest statement

Declaration of Interests J.S.d.B. has served on advisory boards and received fees from companies including Astra Zeneca, Astellas, Bayer, Bioxcel Therapeutics, Boehringer Ingelheim, Cellcentric, Daiichi, Eisai, Genentech/Roche, Genmab, GSK, Janssen, Merck Serono, Merck Sharp & Dohme, Menarini/Silicon Biosystems, Orion, Pfizer, QIAGEN, Sanofi Aventis, Sierra Oncology, Taiho, and Vertex Pharmaceuticals. J.S.d.B. is an employee of The ICR, which has received funding or other support for his research work from AZ, Astellas, Bayer, Cellcentric, Daiichi, Genentech, Genmab, GSK, Janssen, Merck Serono, MSD, Menarini/Silicon Biosystems, Orion, Sanofi Aventis, Sierra Oncology, Taiho, Pfizer, and Vertex and which has a commercial interest in abiraterone, PARP inhibition in DNA repair defective cancers, and PI3K/AKT pathway inhibitors (no personal income). J.S.d.B. was named as an inventor, with no financial interest, for patent 8,822,438. J.S.d.B. has been the CI/PI of many industry sponsored clinical trials. J.S.d.B. is a National Institute for Health Research (NIHR) Senior Investigator. The views expressed in this article are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health.

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