Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2020 Jul 10;99(28):e20776.
doi: 10.1097/MD.0000000000020776.

Femoral nerve block vs adductor canal block after anterior cruciate ligament reconstruction under general anesthesia: A prospective randomized trial protocol

Affiliations
Comparative Study

Femoral nerve block vs adductor canal block after anterior cruciate ligament reconstruction under general anesthesia: A prospective randomized trial protocol

Qingpei Xue et al. Medicine (Baltimore). .

Expression of concern in

  • Expression of Concern: Study Protocols.
    [No authors listed] [No authors listed] Medicine (Baltimore). 2025 Nov 7;104(45):e46330. doi: 10.1097/MD.0000000000046330. Medicine (Baltimore). 2025. PMID: 41204616 Free PMC article. No abstract available.

Abstract

Background: Femoral nerve block (FNB) is considered the preferred analgesia after anterior cruciate ligament reconstruction (ACLR), but leads to weakness in the quadriceps muscles. Adductor canal block (ACB) is a new sensory block technique that effectively relieves postoperative pain while preserving quadriceps strength. The purpose of our study was to compare the efficacy of FNB vs ACB for pain control after ACLR.

Methods: This prospective, randomized, double-blind, controlled, superiority clinical trial was approved by the institutional review board in our university hospital. We enrolled 120 patients set to undergo ACLR in this randomized therapeutic trial. Sixty patients received FNB and the other 60 received ACB for postoperative pain control. All ACB and FNB were performed using ultrasound-guided single-shot procedures. The primary outcomes included maximum voluntary isovolumetric contraction and postoperative pain score. Secondary outcomes included total opioid consumption, length of hospital stay, complication, and satisfaction score.

Results: This clinical trial might provide some insights to estimate and compare the safety and efficacy of ACB vs FNB following ACLR.

Trial registration: This study protocol was registered in Research Registry (researchregistry5569).

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Flow diagram of the study. ACB = adductor canal block, FNB = femoral nerve block.

References

    1. Abdallah FW, Whelan DB, Chan VW, et al. Adductor canal block provides noninferior analgesia and superior quadriceps strength compared with femoral nerve block in anterior cruciate ligament reconstruction. Anesthesiology 2016;124:1053–64. - PubMed
    1. Runner RP, Boden SA, Godfrey WS, et al. Quadriceps strength deficits after a femoral nerve block versus adductor canal block for anterior cruciate ligament reconstruction: a prospective, single-blinded, randomized trial. Orthop J Sports Med 2018;6: 2325967118797990. - PMC - PubMed
    1. El Ahl MS. Femoral nerve block versus adductor canal block for postoperative pain control after anterior cruciate ligament reconstruction: a randomized controlled double blind study. Saudi J Anaesth 2015;9:279–82. - PMC - PubMed
    1. Lynch JR, Okoroha KR, Lizzio V, et al. Adductor canal block versus femoral nerve block for pain control after anterior cruciate ligament reconstruction: a prospective randomized trial. Am J Sports Med 2019;47:355–63. - PubMed
    1. Borys M, Domagała M, Wencław K, et al. Continuous femoral nerve block is more effective than continuous adductor canal block for treating pain after total knee arthroplasty: A randomized, double-blind, controlled trial. Medicine (Baltimore) 2019;98:e17358. - PMC - PubMed

Publication types