Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Jul;61(4):452-454.
doi: 10.4111/icu.2020.61.4.452. Epub 2020 Jun 29.

Letter to the editor: Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer

Abraham Morgentaler  1 , Abdulmaged M Traish  2   3
Affiliations
Comment

Letter to the editor: Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer

Abraham Morgentaler et al. Investig Clin Urol. 2020 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

CONFLICTS OF INTEREST: The authors have nothing to disclose.

Comment on

References

    1. Kim JW. Questioning the evidence behind the Saturation Model for testosterone replacement therapy in prostate cancer. Investig Clin Urol. 2020;61:242–249. - PMC - PubMed
    1. Morgentaler A, Traish AM. Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth. Eur Urol. 2009;55:310–320. - PubMed
    1. Morgentaler A, Benesh JA, Denes BS, Kan-Dobrosky N, Harb D, Miller MG. Factors influencing prostate-specific antigen response among men treated with testosterone therapy for 6 months. J Sex Med. 2014;11:2818–2825. - PubMed
    1. Khera M, Bhattacharya RK, Blick G, Kushner H, Nguyen D, Miner MM. Changes in prostate specific antigen in hypogonadal men after 12 months of testosterone replacement therapy: support for the prostate saturation theory. J Urol. 2011;186:1005–1011. - PubMed
    1. Rastrelli G, Corona G, Vignozzi L, Maseroli E, Silverii A, Monami M, et al. Serum PSA as a predictor of testosterone deficiency. J Sex Med. 2013;10:2518–2528. - PubMed