MEG3 and MEG8 aberrant methylation in an infant with neuroblastoma

Estela M Novak^{1

2

3}, Thamiris M Gimenez^{1

2}, Nathalia H Neves^{1

4}, Carolina C Vince^{1

4}, Ana Cristina V Krepischi⁵, Rainer M Lapa⁶, Lilian M Cristofani¹, Israel Bendit³, Vicente Odone Filho^{1

4}

Affiliations

¹ Instituto de Tratamento de Câncer Infantil, Instituto da Criança, HC/FMUSP, São Paulo, Brazil.
² Laboratório de Investigação Médica (LIM 36), Instituto da Criança, HC/FMUSP, São Paulo, Brazil.
³ Fundação Pró-Sangue Hemocentro de São Paulo, São Paulo, Brazil.
⁴ Hospital Israelita Albert Einstein (HIAE), São Paulo, Brazil.
⁵ Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
⁶ Genetics Department, Biosciences Institute - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.

Case Reports

Estela M Novak et al. Pediatr Blood Cancer. 2020 Sep.

. 2020 Sep;67(9):e28328.

doi: 10.1002/pbc.28328. Epub 2020 Jul 15.

¹ Instituto de Tratamento de Câncer Infantil, Instituto da Criança, HC/FMUSP, São Paulo, Brazil.
² Laboratório de Investigação Médica (LIM 36), Instituto da Criança, HC/FMUSP, São Paulo, Brazil.
³ Fundação Pró-Sangue Hemocentro de São Paulo, São Paulo, Brazil.
⁴ Hospital Israelita Albert Einstein (HIAE), São Paulo, Brazil.
⁵ Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
⁶ Genetics Department, Biosciences Institute - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.

No abstract available

References

1. Irwin MS, Park JR. Neuroblastoma: paradigm for precision medicine. Pediatr Clin North Am. 2015;62:225-256.
1. Ahmed AA, Zhang L, Reddivalla N, Hetherington M. Neuroblastoma in children: update on clinicopathologic and genetic prognostic factors. Pediatr Hematol Oncol. 2017;34:165-185.
1. Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer. 2003;3:203-216.
1. Park JR, Bagatell R, London WB, et al. Children's Oncology Group's 2013 blueprint for research: neuroblastoma. Pediatr Blood Cancer. 2013;60:985-993.
1. Brodeur GM, Pritchard J, Berthold F, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging and response to treatment. J Clin Oncol. 1993;11:1466-1477.