Update Alert: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19

Adrian V Hernandez¹, Yuani M Roman², Vinay Pasupuleti³, Joshuan J Barboza⁴, C Michael White⁵

Affiliations

¹ University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut, School of Pharmacy, Storrs, Connecticut, and Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru (A.V.H.).
² University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut (Y.M.R.).
³ MedErgy HealthGroup, Yardley, Pennsylvania (V.P.).
⁴ Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru (J.J.B.).
⁵ University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut, and School of Pharmacy, Storrs, Connecticut (C.M.W.).

PMID: 32667853
PMCID: PMC7377263
DOI: 10.7326/L20-0945

Comment

Update Alert: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19

Adrian V Hernandez et al. Ann Intern Med. 2020.

. 2020 Aug 18;173(4):W78-W79.

doi: 10.7326/L20-0945. Epub 2020 Jul 15.

Authors

Adrian V Hernandez¹, Yuani M Roman², Vinay Pasupuleti³, Joshuan J Barboza⁴, C Michael White⁵

Affiliations

¹ University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut, School of Pharmacy, Storrs, Connecticut, and Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru (A.V.H.).
² University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut (Y.M.R.).
³ MedErgy HealthGroup, Yardley, Pennsylvania (V.P.).
⁴ Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru (J.J.B.).
⁵ University of Connecticut Health Outcomes, Policy, and Evidence Synthesis Group and Hartford Hospital Department of Research Administration, Hartford, Connecticut, and School of Pharmacy, Storrs, Connecticut (C.M.W.).

PMID: 32667853
PMCID: PMC7377263
DOI: 10.7326/L20-0945

No abstract available

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Conflict of interest statement

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L20-0945.

Comment on

Hydroxychloroquine or Chloroquine for Treatment or Prophylaxis of COVID-19: A Living Systematic Review.
Hernandez AV, Roman YM, Pasupuleti V, Barboza JJ, White CM. Hernandez AV, et al. Ann Intern Med. 2020 Aug 18;173(4):287-296. doi: 10.7326/M20-2496. Epub 2020 May 27. Ann Intern Med. 2020. PMID: 32459529

References

1. Hernandez AV, Roman YM, Pasupuleti V, et al. Hydroxychloroquine or chloroquine for treatment or prophylaxis of COVID-19: a living systematic review. Ann Intern Med. 2020. [PMID: 32459529] doi:10.7326/M20-2496 - PubMed
1. Tang W, Cao Z, Han M, et al. Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial. BMJ. 2020;369:m1849. [PMID: 32409561] doi:10.1136/bmj.m1849 - PMC - PubMed
1. Mahévas M, Tran VT, Roumier M, et al. Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data. BMJ. 2020;369:m1844. [PMID: 32409486] doi:10.1136/bmj.m1844 - PMC - PubMed
1. Yu B, Li C, Chen P, et al. Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19. Sci China Life Sci. 2020. [PMID: 32418114] doi:10.1007/s11427-020-1732-2 - PMC - PubMed
1. Chen L, Zhang ZY, Fu JG, et al. Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study. medRxiv. Preprint posted online 22 June 2020. doi:10.1101/2020.06.19.20136093

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Update Alert: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19

Affiliations

Update Alert: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19

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