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. 2021 Jan;41(1):24-31.
doi: 10.1038/s41372-020-0730-1. Epub 2020 Jul 15.

Epidemiology of readmissions in early infancy following nonelective cesarean delivery

Namasivayam Ambalavanan  1 , Victoria Jauk  2 , Jeff M Szychowski  2   3 , Kim A Boggess  4 , George Saade  5 , Sherri Longo  6 , Sean Esplin  7 , Kirsten Cleary  8 , Ronald Wapner  8 , Kellett Letson  9 , Michelle Owens  10 , Sean Blackwell  11 , William Andrews  3 , Alan T Tita  3 ; C/SOAP Consortium
Collaborators, Affiliations

Epidemiology of readmissions in early infancy following nonelective cesarean delivery

Namasivayam Ambalavanan et al. J Perinatol. 2021 Jan.

Abstract

Objective: Determine incidence and risk factors for readmissions in early infancy.

Study design: Secondary analysis of data from the Cesarean Section Optimal Antibiotic Prophylaxis trial. All unplanned revisits (unplanned clinic, ER visits, and hospital readmissions) and hospital readmissions (initial discharge to 3-month follow-up) were analyzed.

Results: 295 (15.9%) of 1850 infants had revisits with risk factors being ethnicity (adjusted odds ratio (aOR): 0.6 for Hispanic), maternal postpartum antibiotics (1.89), azithromycin treatment (1.22), small for gestational age (1.68), apnea (3.82), and hospital stay after birth >90th percentile (0.49). 71 (3.8%) of 1850 infants were readmitted with risk factors being antenatal steroids (aOR 2.49), elective repeat C/section (0.72), postpartum maternal antibiotics (2.22), O2 requirement after delivery room (2.82), and suspected/proven neonatal sepsis (0.55).

Conclusion(s): Multiple risk factors were identified, suggesting potential impact on the neonatal microbiome (maternal postpartum antibiotics) or issues related to access/cost of care (Hispanic ethnicity associated with fewer revisits).

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Conflict of interest statement

Conflict of interest: The authors have no financial relationships or conflicts of interest relevant to this article to disclose.

Figures

Figure 1:
Figure 1:
Flow diagram of patient enrollment
See this image and copyright information in PMC

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